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Description
TIE2 His Tag Protein, MouseProduct Specification Species Mouse Synonyms TIE2, Tie 2, TEK, VMCM, VMCM1, CD202b, Angiopoietin 1 receptor Accession Q02858 Amino Acid Sequence Ala23 Leu746, with C 8*His Expression System HEK293 Molecular Weight 92 107kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water
Product Specification
| Species | Mouse |
| Synonyms | TIE2, Tie-2, TEK, VMCM, VMCM1, CD202b, Angiopoietin-1 receptor |
| Accession | Q02858 |
| Amino Acid Sequence | Ala23-Leu746, with C-8*His |
| Expression System | HEK293 |
| Molecular Weight | 92-107kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Jones N. et al. (1998) The Tek / Tie2 receptor signals through a novel Dok-related docking protein, Dok-R. Oncogene. 17(9): 1097-1108. 2、Sato A. et al. (1998) Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor cells. Int Immunol. 10(8): 1217-1227. |
Background
Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis.
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4.5 ★★★★★
Based on 2063 reviews
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Product Reviews
★★★★★ 3
No bow tie
Color: Burgundy, Size: XX-Large
Perfect fit for my son he's 6'2" about 220lbs. He ordered 2XL . I would've gave it 5 stars but he did not receive the bow tie, and his prom is tomorrow! Now I gotta go out snd spend more money buying the bow tie separately.
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Reviewed in the United States on May 22, 2026
★★★★★ 5
Sharp suit
Color: Black, Size: X-Small, Color: Black, Size: X-Small
The quality of the suit is very nice. The material feels thick and does not feel cheap at all. My son and I were both very pleased with this three piece suit altogether. We went off of size recommendation and due to personal preference we both agreed if we weren’t already in time crunch we would’ve sized up one size. Still managed to make it work and looked very sharp.
He is 5’10” 150lbs - size ordered extra small
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Reviewed in the United States on June 5, 2026
★★★★★ 5
Great shirt
Size: Large, Color: Grey
Great shirt with a good price ..nice fit & nice material . Looks great when ironed !!
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Reviewed in the United States on April 1, 2026
★★★★★ 5
Wonderful product
Size: Large, Color: Sky Blue
Great Shirts this is the second set I have bought and they wear nicely and fit well
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Reviewed in the United States on April 15, 2026
★★★★★ 4
Order 1 size larger.
Size: X-Large, Color: Blue White Plaid
Nice shirt. The size is not accurate by any stretch of the imagination. I wear size xl in shirts except for this one. An xl fits like a large. Other than that I like the shirt. I would've given it 5 stars if not for the sizing. I'll give away this one and order an xxl. Just order a size above what you wear and you'll be happy.
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Reviewed in the United States on February 15, 2026